4 Best CBD Oil for Nerve Pain & Neuropathy (2023)

Best CBD Oil for Nerve Pain & Neuropathy

Nerve pain is also referred to as neuropathy or peripheral neuropathy, which is defined as “any condition that affects the normal activity of the nerves of the peripheral nervous system,”.

The network of nerves in the human body known as the peripheral nervous system connects the central nervous system, the spine, and the brain, to the rest of your body. It is made up of three kinds of nerves including, motor nerves, sensory nerves, and autonomic nerves.

Due to how painful neuropathy is, CBD oil for nerve pain research and studies may discover how this treatment may relieve neuropathy.

Best CBD Oil for Nerve Pain

Verma Farms
Royal CBD
Absolute Nature
NuLeaf Naturals
Hemp Bombs

1. Verma Farms

Verma Farms

When it comes to finding a good CBD oil company to help with nerve pain, it’s going to be hard to beat Verma Farms. This completely natural, 100% organic CBD oil company is passionate about sharing the good news with its clients, which is why it has so far won many different awards for its products.

Originally it started out as just a CBD gummy company but has since expanded its operation to include CBD oil, topical creams, CBD for pets, CBD capsules, and CBD dried fruit.

They never include any THC in any of their products, so you don’t have to worry about getting high as a result. They offer free shipping on their American orders and considering they grow their hemp on organic hemp farms in Hawaii, we think that it’s worth supporting this native brand.

They are constantly thinking about how they can improve their line for their clients, so if you’ve been suffering from nerve pain for a while and you’re looking for a practical way to deal with it, then we highly recommend that you check out Verma Farms.

2. Royal CBD

Royal CBD

If you have nerve pain and you want to try and get rid of it the all-natural way, then you need to check out Royal CBD.

This company has been around for a while now, and focuses on providing their clients with organic hemp extracts as well as non-GMO CBD products, so that you can benefit from the full-spectrum powers of CBD, but ensure that it’s pure at the same time.

They are one of the best companies in the CBD oil industry, so much so that they have been named as such, and you can easily buy their products on their website, which is user friendly.

We love that they offer their clients free shipping within America, and they are consistent about delivering only the best products to their clients.

They also talk about how they batch test every one of their products and send them through a third-party lab so that you can make sure you are staying away from solvents, heavy metals, and toxins. F

rom CBD capsules to oil and even gummies, these guys have it all. They even have products for your pet.

3. Zion


Zion claims to have some of the world’s finest CBD products, and honestly, we don’t think that they’re far off the mark. In fact, they have been market leaders since 2014, which is saying a lot considering most of the industry is unregulated.

They are proud that all of their CBD products are made in the USA, and they offer free and fast shipping around the world. They have an expansive range of products for their clients, including CBD oil tinctures, capsules, creams, gummies, sprays, and pet products.

If you’re someone who loves reading up on reviews like this one before you try something, then we can confidently say that Zion has more than 51 five-star reviews on Trustpilot, a third-party review forum.

They have been featured on many different media outlets including the New York Times, CNN, and HuffPost, and give back through their Veterans assistance program. Their products are certified organic, non-GMO, gluten-free, and made in the USA.

4. Absolute Nature

Absolute Nature CBD

Absolute Nature is a CBD oil brand that has been around for a while, and they have spent a lot of time in other health-related industries as well, including the natural supplement industry.

They have brought their expertise over, and as a result have some of the best CBD products that you could hope for.

We love that they have hundreds of reviews that they have collected from existing clients too, so you know that their products are backed up by real, satisfied clients.

They want to make sure that they are doing the earth a favor as well with their environmentally-friendly practices, and every ingredient that they include in their products is organic, and produced organically.

If you are relatively new to the world of CBD, this is a great place to begin, and if you’re not satisfied for some reason, they can give you your money back because they offer their clients a two-week return policy.

They have CBD oil, softgels, gummies, and topicals on offer, and they have proof that they test every batch that they manufacture, so that you can feel confident that you’ll only find the best of the best in their CBD products.

About Nerve Pain

Neuropathy happens when the body’s neurons or nerve cells become damaged or destroyed. The most common causes are traumatic injury, autoimmune disorders, infections, diseases like diabetes, vascular disorders, medications, poison, vitamin deficiencies, or alcoholism.

According to the Cleveland Clinic, neuropathy is quite common, affecting between 25 and 30 percent of Americans.

The percentage of people with diabetes is between 60 and 70 percent. Healthengine.com.au reports that one in five Australians suffer from chronic pain and that many of these individuals have some form of nerve pain associated with their chronic pain.

Symptoms of Nerve Pain

Nerve Pain

The symptoms of nerve pain vary somewhat between the type of nerves that are affected. The common symptoms of each of the three types of nerve pain include:

Motor Neuropathy

  • Muscle weakness and/or twitching
  • Difficulty with moving your arms or legs or walking
  • Loss of muscle tone and control
  • Loss of manual dexterity
  • The inability to move a body part

Sensory Neuropathy

  • Numbness and/or tingling in their hands and feet
  • Changes in sensations varying from being unable to feel pain, temperature, touch, or pressure to suffering severe pain in the evening and night
  • Loss of reflexes and coordination
  • The feeling that you are wearing gloves or socks when you are not.
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Autonomic Neuropathy

  • Issues with urination
  • Digestive problems
  • Sexual dysfunction
  • Decreased sweating
  • Abnormal heart rate or blood pressure
  • Nausea or vomiting
  • Unintentional weight loss
  • Feeling faint or dizzy when standing up

When medical science cannot find the cause for nerve pain, they refer to that as idiopathic neuropathy. Between 30 and 40 percent of Americans suffer from idiopathic neuropathy.

The FDA has an overview of neuropathy, nerve pain, that comes from the perspective of the patient.

Research regarding CBD oil for nerve pain is still in its infancy, but some promising reports along with the problems of using cannabis for nerve pain have been made. This study includes the use of CBD oil and THC cannabis.

What Causes Neuropathic Pain?

Neuropathic Pain

Neurons that are found in the body carry important signals to the brain, including pain signals. While nobody likes to be in pain, there is an important reason for this – to prevent you from getting injured.

For example, when you place your foot on a surface that is hot, the painful sensation will carry to your brain and prevent you from getting hurt even more.

This is how the process of signals being sent to your brain about pain is supposed to work in normal, healthy people. However, if you experience neuropathic pain, your nervous system goes completely haywire, which means that the signaling system isn’t able to work as normal.

This means that your brain might receive signals still about pain, and you feel the sensation of pain, but there is no obvious cause for this. This is why it is typically difficult to solve. So, how can this happen?

Let’s take a look at a few reasons why you might be suffering from neuropathic pain.

  • Physical Injury: this is potentially the most common cause of neuropathic pain. When someone is injured in any kind of way, the nerves can get severed, compressed, or crushed, which can interfere with those signals working as normal.
  • Shingles: if you suffer from shingles, a disease that is mostly found in adults, this can be another cause for the neuropathy that you suffer from. If these two are combined, the result can often be a far more painful condition called postherpetic neuralgia. This particular kind of nerve pain can be immediate and severe.
  • Tumors and Cancer: as tumors grow in the body, they can put pressure on the nerves that surround it. Cancer cells can also grow out of nerves as well, which directly impacts when the nerves send signals to the brain. A lot of the time, if you are receiving chemotherapy for your cancer or tumor, this can end up damaging the surrounding nerves, which might result in neuropathic pain.
  • HIV: if you have HIV, an autoimmune viral condition, then this could lead to nerve damage causing severe pain. Nerve pain actually affects up to two thirds of HIV patients, and painful sensations in both the hands and feet are the most common, and some of the first symptoms that will appear. Treatments associated with HIV can be used to help with the nerve damage that triggers pain.
  • Diabetes: if you suffer from diabetes, then you might have a higher risk of experience nerve damage or injury. This is because if you have high levels of glucose combined with hypertension, this can end up damaging the nerves.

There are a few reasons why you might be suffering from nerve damage that we have discussed above, but there are a lot more out there.

Other potential causes include viral infections, surgery or trauma, alcoholism, vascular malformations, multiple sclerosis, vitamin deficiencies, hormone balances, and ongoing exposure to high levels of stress. In some extremely rare cases, nerve pain can develop without any obvious cause.

How Can You Determine the Cause of Neuropathic Pain?

Cause of Neuropathic Pain

To determine the cause of neuropathic pain, doctors will first sit down with the patient and ask a series of questions, asking about medical condition history, current symptoms, and they might even carry out a short medical examination.

Your healthcare professional may check for things including sensory loss by using a pinprick on various parts of the body.

If the patient has a low sensory response or no response at all to the pinprick, then they might be suffering from neuropathic pain.

Apart from conducting an initial interview, you doctor may advise you to get additional testing, including bloodwork, so that they can work out the exact reason behind the nerve pain and damage in your circumstance.

They might ask you to carry out a blood test that looks for blood sugar levels, in order to eliminate the possibility of diabetes.

Your healthcare professional might also check if you have good vitamin B12 levels, as deficiencies in vitamins like this can lead to nerve numbness and damage.

Treatment Options for Nerve Pain

Treatment for Nerve Pain

It is difficult to treat issues like neuropathy because of the exact nature of the symptoms, as well as the cause of the issue. When nerve pain is triggered by things like diabetes, cancer, or HIV, getting to the bottom of the disease and tackling it head-on is a big priority.

However, while nerve pain might require dedicated treatment, it is difficult to treat a disease that has very little known about the cause.

Apart from CBD, healthcare professionals will typically prescribe painkillers depending on the severity and type of neuropathic pain. However, most people are at risk of building up a tolerance to medication like this, as well as the potential risk of addiction and adverse side effects, including overdose.

Experts believe that there are more than 40 million Americans that struggle with nerve pain. This means that the direct impact of neuropathy on Western society is huge, and for most of us, the adverse side effects of harmful medications outweigh the potential benefits.

This is why a lot of people eventually choose to look elsewhere for help managing nerve damage pain, and a lot of the time that is CBD oil.

CBD oil can be used to treat many different types of physical pain.

CBD vs. Anxiety, Chronic Pain, and Nausea

In line with the American Chronic Pain Association, neuropathic pain is chronic pain that comes with many telltale symptoms.

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These include vomiting, nausea, pain, and anxiety. Research indicates that CBD might be useful in helping combat different kinds of chronic pain that come with symptoms including nausea and anxiety.

CBD also has a number of anti-inflammatory effects that can help with chronic symptoms including relieving muscles spasms which is often seen as a common side effect of ongoing nerve issues.

Whether you are an advocate for natural remedies or not, it’s clear that there is already substantial evidence to back up the fact that CBD is an excellent natural alternative to often much harsher pharmaceutical options out there.

Pros and Cons of Using CBD Oil for Neuropathy

Just like with any treatment, there are pros and cons associated with using CBD oil for nerve pain or neuropathy.

  • Can help with symptoms like the ones we have discussed above, including pain, vomiting, inflammation and anxiety.
  • Isn’t addictive.
  • Doesn’t come with THC so isn’t intoxicating.
  • Recognized by WHO as a safe, natural remedy.
  • Can be bought without a prescription, either in store or online.
  • Not officially approved by the FDA as an effective treatment.
  • Side effects include fatigue, drowsiness, dry mouth and fluctuation of appetite.
  • The industry is largely unregulated.

What Is CBD Oil?

Before learning how CBD oil for nerve pain works, you first need to what CBD oil is. A common misconception about CBD oil is that it is just like marijuana or medical marijuana.

Cannabidiol and delta-9-tetrahydrocannabinol are two of the several types of cannabinoids found in marijuana. The biggest difference between the two is that Cannabidiol (CBD) produces no psychoactive effects whereas, THC does.

In other words, THC is the active ingredient that gets you “high”, but CBD offers similar results without the “high”.

The main reason for this is that while both CBD and THC interact with CB1 and CB2 receptors in the human body, they interact with different receptors in the human brain.

What Are Some Benefits of CBD Oil for Nerve Pain?

CBD oil

CBD oil is believed to help people in a variety of ways.

  • Keeps you calm during undue stress
  • Aids in the navigation of everyday stress
  • Reduces inflammation after working out
  • Reduces insomnia and sleep disruptions
  • It helps combat cold weather dry skin

Is CBD Oil for Nerve Pain Legal?


Currently, in most of the United States, the legal status of CBD oil is constantly changing. While all 50 states have different levels of restriction, the federal government still has CBD oil in the same illegal category as marijuana, but they don’t often enforce it.

It was only at the end of 2015 that the Food and Drug Administration (FDA) eased up on its regulatory requirements so that CBD trials can be conducted. Most of the legality of CBD oil in the United States revolves around which plant is used in the manufacturing of CBD oil.

It is believed that the United States government will make hemp crops legal, which would open the doors for CBD oil since the hemp plant is high in CBD and very low in THC.

Are There Side Effects of Using CBD Oil for Nerve Pain?

CBD oil may cause fatigue, irritability, or nausea, or vomiting, but these side effects are considered mild. However, if you take a blood thinner like coumadin, it may increase its effect. It may also raise the levels of other medications, which is one reason to consult with your doctor before trying CBD oil.

If you are not already a label reader, become one. The FDA does not regulate the purity or safety of supplements, so you cannot know whether the CBD oil for nerve pain is pure.

What Studies Have Shown Promise for Using CBD Oil for Nerve Pain?

CBD oil for nerve pain

What is known about CBD oil is that it is effective for reducing or preventing seizures in epilepsy patients with Lennox-Gastaut syndrome (LGS) and Dravet syndrome, which are types of epilepsy known to not respond to conventional antiseizure medications.

Epidiolex, a cannabis-derived medication, has recently been approved by the FDA for these seizure disorders.

That is good news for people suffering from anxiety, insomnia, chronic pain, arthritis, and even neuropathy. While more human studies are needed for the efficacy of CBD oil for nerve pain, there are some that show promise in the area.

This article, “Cannabis for peripheral neuropathy: The good, the bad, and the unknown” in the Cleveland Clinic Journal of Medicine authored by Vania Modesto-Lowe, MD, MPH; Rachel Bojka, MS, PA-C; and Camille Alvarado, DO, MPH, points out some of the research and studies performed on CBD oil for nerve pain.

“Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptor”, an article written by Wei Xiong, Tanxing Cui, Kejun Cheng, Shao-Rui Chen, Dan Willenbring, Yun Guan, Hui-Lin Pan, Ke Ren, Yan Xu, and Li Shang and published in the Journal of Experimental Medicine, addresses how non-psychoactive cannabinoids interact with the α3 GlyRs.

These two studies could be the start of future studies that may give hope to those suffering from nerve pain.


Until more human studies and clinical trials can be conducted, CBD oil for nerve pain will likely remain up for debate between medical professionals and scientists.

Dr. Rachna Patel reported some positive results for her own patients in this answer she wrote to a person with diabetic neuropathy:

While there are some known benefits, as discussed in this article, of CBD oil, there is still much to be learned before CBD oil for nerve pain can be considered a viable alternative to opioids.

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